diff --git a/scd/ccid-driver.c b/scd/ccid-driver.c
index 7319ada41..39e45a0ab 100644
--- a/scd/ccid-driver.c
+++ b/scd/ccid-driver.c
@@ -1805,7 +1805,10 @@ ccid_open_usb_reader (const char *spec_reader_name,
     }
 
   /* Submit SET_INTERFACE control transfer which can reset the device.  */
-  rc = libusb_set_interface_alt_setting (idev, ifc_no, set_no);
+  if ((*handle)->id_vendor == VENDOR_ACR && (*handle)->id_product == ACR_122U)
+    rc = 0;  /* Not supported by this reader.  */
+  else
+    rc = libusb_set_interface_alt_setting (idev, ifc_no, set_no);
   if (rc)
     {
 #ifdef USE_NPTH
@@ -1820,6 +1823,7 @@ ccid_open_usb_reader (const char *spec_reader_name,
   npth_protect ();
 #endif
 
+  /* Perform any vendor specific intialization.  */
   rc = ccid_vendor_specific_init (*handle);
 
  leave:
diff --git a/scd/ccid-driver.h b/scd/ccid-driver.h
index 18cbc87f0..bac5fac07 100644
--- a/scd/ccid-driver.h
+++ b/scd/ccid-driver.h
@@ -70,6 +70,7 @@ enum {
   VENDOR_FSIJ   = 0x234b,
   VENDOR_VASCO  = 0x1a44,
   VENDOR_NXP    = 0x1fc9,
+  VENDOR_ACR    = 0x072f
 };
 
 
@@ -88,6 +89,7 @@ enum {
 #define VEGA_ALPHA      0x0008
 #define CYBERJACK_GO    0x0504
 #define CRYPTOUCAN      0x81e6
+#define ACR_122U        0x2200    /* NFC Reader */
 
 #endif /*CCID_DRIVER_INCLUDE_USB_IDS*/