diff --git a/dev-python/interleave/Manifest b/dev-python/interleave/Manifest
new file mode 100644
index 0000000..1f4b8f7
--- /dev/null
+++ b/dev-python/interleave/Manifest
@@ -0,0 +1 @@
+DIST interleave-0.2.0.tar.gz 15879 SHA256 3f9b36057dc1e041affe4fe76bac5256a9f7a02f05112b6162bf91ff4e46bb5d SHA512 ed47603fb0b917e7355c9e461584b5c92ba4beef2416e602da0c8b70f36d9d5d5bc57fa3a71bb00e96e35bd580873dca10cdd19280ace7b717765a8386576a0f WHIRLPOOL c3083f2aef832f70b2a228dad6a304729cd55bd8dc759e158e6db58a0d68eb076c87e5ca44cf724044d953504368e9e9ebad930e94560d1bde4f6b71375c5384
diff --git a/dev-python/interleave/files/interleave-0.2.0-drop-coverage.patch b/dev-python/interleave/files/interleave-0.2.0-drop-coverage.patch
new file mode 100644
index 0000000..5f358f6
--- /dev/null
+++ b/dev-python/interleave/files/interleave-0.2.0-drop-coverage.patch
@@ -0,0 +1,18 @@
+--- a/tox.ini
++++ b/tox.ini
+@@ -8,8 +8,6 @@
+ passenv = CI
+ deps =
+     pytest~=7.0
+-    pytest-cov~=3.0
+-    pytest-rerunfailures~=10.0
+ commands =
+     pytest {posargs} test
+
+@@ -31,7 +29,6 @@
+     mypy src test
+
+ [pytest]
+-addopts = --cov=interleave --no-cov-on-fail
+ filterwarnings = error
+ norecursedirs = test/data
diff --git a/dev-python/interleave/files/pycryptodome-3.10.1-system-libtomcrypt.patch b/dev-python/interleave/files/pycryptodome-3.10.1-system-libtomcrypt.patch
new file mode 100644
index 0000000..51a5766
--- /dev/null
+++ b/dev-python/interleave/files/pycryptodome-3.10.1-system-libtomcrypt.patch
@@ -0,0 +1,50 @@
+diff -dupr a/setup.py b/setup.py
+--- a/setup.py	2021-02-09 13:49:46.356455141 +0100
++++ b/setup.py	2021-02-09 13:50:49.351076275 +0100
+@@ -367,13 +367,15 @@ ext_modules = [
+         sources=["src/CAST.c"],
+         py_limited_api=True),
+     Extension("Crypto.Cipher._raw_des",
+-        include_dirs=['src/', 'src/libtom/'],
++        include_dirs=['src/'],
+         sources=["src/DES.c"],
+-        py_limited_api=True),
++        py_limited_api=True,
++        extra_link_args=["-ltomcrypt"]),
+     Extension("Crypto.Cipher._raw_des3",
+-        include_dirs=['src/', 'src/libtom/'],
++        include_dirs=['src/'],
+         sources=["src/DES3.c"],
+-        py_limited_api=True),
++        py_limited_api=True,
++        extra_link_args=["-ltomcrypt"]),
+     Extension("Crypto.Util._cpuid_c",
+         include_dirs=['src/'],
+         sources=['src/cpuid.c'],
+@@ -410,9 +412,10 @@ ext_modules = [
+         sources=["src/ARC4.c"],
+         py_limited_api=True),
+     Extension("Crypto.Cipher._Salsa20",
+-        include_dirs=['src/', 'src/libtom/'],
++        include_dirs=['src/'],
+         sources=["src/Salsa20.c"],
+-        py_limited_api=True),
++        py_limited_api=True,
++        extra_link_args=["-ltomcrypt"]),
+     Extension("Crypto.Cipher._chacha20",
+         include_dirs=['src/'],
+         sources=["src/chacha20.c"],
+Only in b: setup.py.orig
+Only in b: setup.py.rej
+diff -dupr a/src/DES.c b/src/DES.c
+--- a/src/DES.c	2021-02-09 13:49:46.336454729 +0100
++++ b/src/DES.c	2021-02-09 13:50:02.640123617 +0100
+@@ -39,7 +39,7 @@ FAKE_INIT(raw_des3)
+ 
+ /* Include the actial DES implementation */
+ #define LTC_NO_PROTOTYPES
+-#include "libtom/tomcrypt_des.c"
++#include <tomcrypt.h>
+ 
+ struct block_state {
+     symmetric_key sk;
diff --git a/dev-python/interleave/interleave-0.2.0.ebuild b/dev-python/interleave/interleave-0.2.0.ebuild
new file mode 100644
index 0000000..c8a9c9c
--- /dev/null
+++ b/dev-python/interleave/interleave-0.2.0.ebuild
@@ -0,0 +1,25 @@
+# Copyright 1999-2022 Gentoo Authors
+# Distributed under the terms of the GNU General Public License v2
+
+EAPI=8
+
+DISTUTILS_USE_PEP517=setuptools
+PYTHON_COMPAT=( python3_{8..10})
+
+inherit distutils-r1
+
+DESCRIPTION="Yield from multiple iterators as values become available"
+HOMEPAGE="https://github.com/jwodder/interleave"
+SRC_URI="mirror://pypi/${P:0:1}/${PN}/${P}.tar.gz"
+
+LICENSE="MIT"
+SLOT="0"
+KEYWORDS="~amd64 ~arm ~arm64 ~x86 ~amd64-linux ~x86-linux"
+
+RDEPEND="
+	dev-python/wheel[${PYTHON_USEDEP}]
+"
+
+PATCHES=( "${FILESDIR}/${PN}-0.2.0-drop-coverage.patch" )
+
+distutils_enable_tests pytest
diff --git a/dev-python/interleave/metadata.xml b/dev-python/interleave/metadata.xml
new file mode 100644
index 0000000..66b4383
--- /dev/null
+++ b/dev-python/interleave/metadata.xml
@@ -0,0 +1,21 @@
+<?xml version='1.0' encoding='UTF-8'?>
+<!DOCTYPE pkgmetadata SYSTEM "http://www.gentoo.org/dtd/metadata.dtd">
+<pkgmetadata>
+	<maintainer type="person">
+		<email>gentoo@chymera.eu</email>
+		<name>Horea Christian</name>
+	</maintainer>
+	<maintainer type="project">
+		<email>sci@gentoo.org</email>
+		<name>Gentoo Science Project</name>
+	</maintainer>
+	<longdescription lang="en">
+		The interleave package provides a function of the same name that
+		takes a number of iterators, runs them in separate threads, and
+		yields the values produced as soon as each one is available.
+	</longdescription>
+	<upstream>
+		<remote-id type="github">jwodder/interleave</remote-id>
+		<remote-id type="pypi">interleave</remote-id>
+	</upstream>
+</pkgmetadata>