diff --git a/dev-python/wxpython/Manifest b/dev-python/wxpython/Manifest
new file mode 100644
index 0000000..e2539a6
--- /dev/null
+++ b/dev-python/wxpython/Manifest
@@ -0,0 +1 @@
+DIST wxpython-4.0.3.tar.gz 68545642 SHA256 8d0dfc0146c24749ce00d575e35cc2826372e809d5bc4a57bde6c89031b59e75 SHA512 911dd98d15b0cbc2551f1b22a21fdae4450656ca59cc93216b7c6a8a00e399b929b78484637992d78cecffb098b8d8dc408c24795549827e2f90ce42740c3bf9 WHIRLPOOL 816126c9d37e3f3d3c2ca11e3e7f4aeed027afc0b3d3fb51b2115d4d73aa98f2ef897e6d16b1dfe80333ab5f84de90a0a42b41676607b90a0ce1edb9e68f60be
diff --git a/dev-python/wxpython/metadata.xml b/dev-python/wxpython/metadata.xml
new file mode 100644
index 0000000..f6588d2
--- /dev/null
+++ b/dev-python/wxpython/metadata.xml
@@ -0,0 +1,18 @@
+<?xml version="1.0" encoding="UTF-8"?>
+<!DOCTYPE pkgmetadata SYSTEM "http://www.gentoo.org/dtd/metadata.dtd">
+<pkgmetadata>
+	<maintainer type="project">
+		<email>wxwidgets@gentoo.org</email>
+		<name>Gentoo wxWidgets Project</name>
+	</maintainer>
+	<maintainer type="project">
+		<email>python@gentoo.org</email>
+		<name>Python</name>
+	</maintainer>
+	<use>
+		<flag name="examples">Install interactive demo module browser and sample applets.</flag>
+	</use>
+	<upstream>
+		<remote-id type="sourceforge">wxpython</remote-id>
+	</upstream>
+</pkgmetadata>
diff --git a/dev-python/wxpython/wxpython-4.0.3.ebuild b/dev-python/wxpython/wxpython-4.0.3.ebuild
new file mode 100644
index 0000000..f3dabe1
--- /dev/null
+++ b/dev-python/wxpython/wxpython-4.0.3.ebuild
@@ -0,0 +1,61 @@
+# Copyright 1999-2017 Gentoo Foundation
+# Distributed under the terms of the GNU General Public License v2
+
+EAPI=6
+
+PYTHON_COMPAT=( python2_7 python3_{4,5,6} )
+WX_GTK_VER="3.0"
+
+inherit distutils-r1 wxwidgets
+
+P_HASH="bd55ab40e406a026a7fda0bb5eb61f466682544ae91ac26267c750f5e618"
+MY_PN="wxPython"
+
+DESCRIPTION="A blending of the wxWindows C++ class library with Python"
+HOMEPAGE="http://www.wxpython.org/"
+SRC_URI="https://files.pythonhosted.org/packages/dd/31/${P_HASH}/${MY_PN}-${PV}.tar.gz -> ${P}.tar.gz"
+
+LICENSE="wxWinLL-3"
+SLOT="3.0"
+KEYWORDS="~amd64 ~x86"
+IUSE="test"
+
+RDEPEND="
+	dev-python/appdirs[${PYTHON_USEDEP}]
+	dev-python/numpy[${PYTHON_USEDEP}]
+	dev-python/pillow[${PYTHON_USEDEP}]
+	dev-python/pypubsub[${PYTHON_USEDEP}]
+	dev-python/requests[${PYTHON_USEDEP}]
+	dev-python/six[${PYTHON_USEDEP}]
+	dev-python/sphinx[${PYTHON_USEDEP}]
+	dev-python/twine[${PYTHON_USEDEP}]
+	dev-python/wheel[${PYTHON_USEDEP}]
+"
+
+DEPEND="
+	dev-python/pip[${PYTHON_USEDEP}]
+	dev-python/setuptools[${PYTHON_USEDEP}]
+	test? (
+		${RDEPEND}
+		dev-python/pytest[${PYTHON_USEDEP}]
+	)
+"
+
+S="${WORKDIR}/${MY_PN}-${PV}"
+
+python_prepare_all() {
+	if use test; then
+		# Errors reported upstream: https://github.com/wxWidgets/Phoenix/issues/1025
+		sed -i \
+			-e "/class GetAutoCompleteListTestCase(GetAttributeTestCase):/i@unittest.skip('Known to fail')" \
+			-e "/class GetAttributeNamesTestCase(GetAttributeTestCase):/i@unittest.skip('Known to fail')" \
+			wx/py/tests/test_introspect.py || die
+	fi
+	distutils-r1_python_prepare_all
+}
+
+python_test() {
+	distutils-r1_install_for_testing
+	cd "${BUILD_DIR}/lib/wx/py/tests" || die
+	${EPYTHON} -m unittest discover || die
+}