diff --git a/dev-python/hdbscan/ChangeLog b/dev-python/hdbscan/ChangeLog
new file mode 100644
index 0000000..2841a7d
--- /dev/null
+++ b/dev-python/hdbscan/ChangeLog
@@ -0,0 +1,4 @@
+*hdbscan-0.8.26 (12 Oct 2021)
+
+  12 Oct 2021;  <chymera@gentoo.org> +hdbscan-0.8.26.ebuild, +metadata.xml:
+  dev-python/hdbscan: new package (DANDI ephys stack)
diff --git a/dev-python/hdbscan/Manifest b/dev-python/hdbscan/Manifest
new file mode 100644
index 0000000..fbf3307
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+++ b/dev-python/hdbscan/Manifest
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+DIST hdbscan-0.8.26.tar.gz 10776639 SHA256 2fd10906603b6565ee138656b6d59df3494c03c5e8099aede400d50b13af912b SHA512 7337f4246511d22e8e11308e7776aad6929f26674daecc1e174b01673782837815a40820a6565406315b1ae14ed059c4945810ac997abfde9e24abda352de622 WHIRLPOOL 792b2cfb440a5cfd17ef66c32418a1f59f5184a72e27c7afcb59433f51a4f6e432ef35cc91c5c6f4117c85d918a4a886ab99552b93b94e7cbcc5e5601aa31fef
diff --git a/dev-python/hdbscan/hdbscan-0.8.26.ebuild b/dev-python/hdbscan/hdbscan-0.8.26.ebuild
new file mode 100644
index 0000000..1284f12
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+++ b/dev-python/hdbscan/hdbscan-0.8.26.ebuild
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+# Copyright 2021 Gentoo Authors
+# Distributed under the terms of the GNU General Public License v2
+
+EAPI=8
+
+PYTHON_COMPAT=( python3_{8..10} )
+inherit distutils-r1
+
+DESCRIPTION="A high performance implementation of HDBSCAN clustering."
+HOMEPAGE="https://github.com/scikit-learn-contrib/hdbscan"
+SRC_URI="https://github.com/scikit-learn-contrib/hdbscan/archive/refs/tags/${PV}.tar.gz -> ${P}.tar.gz"
+
+LICENSE="BSD"
+SLOT="0"
+KEYWORDS="~amd64 ~x86"
+IUSE="test"
+RESTRICT="test"
+# Tests fail, reported to upstream
+# https://github.com/scikit-learn-contrib/hdbscan/issues/501
+
+DEPEND=""
+RDEPEND="
+	dev-python/cython[${PYTHON_USEDEP}]
+	dev-python/joblib[${PYTHON_USEDEP}]
+	dev-python/numpy[${PYTHON_USEDEP}]
+	dev-python/scipy[${PYTHON_USEDEP}]
+	dev-python/six[${PYTHON_USEDEP}]
+	sci-libs/scikit-learn[${PYTHON_USEDEP}]
+"
+BDEPEND=""
+
+distutils_enable_tests pytest
diff --git a/dev-python/hdbscan/metadata.xml b/dev-python/hdbscan/metadata.xml
new file mode 100644
index 0000000..b43e627
--- /dev/null
+++ b/dev-python/hdbscan/metadata.xml
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+<?xml version='1.0' encoding='UTF-8'?>
+<!DOCTYPE pkgmetadata SYSTEM "http://www.gentoo.org/dtd/metadata.dtd">
+<pkgmetadata>
+	<maintainer type="person">
+		<email>gentoo@chymera.eu</email>
+		<name>Horea Christian</name>
+	</maintainer>
+	<maintainer type="project">
+		<email>sci@gentoo.org</email>
+		<name>Gentoo Science Project</name>
+	</maintainer>
+	<longdescription lang="en">
+		HDBSCAN - Hierarchical Density-Based Spatial Clustering of Applications with
+		Noise. Performs DBSCAN over varying epsilon values and integrates the result
+		to find a clustering that gives the best stability over epsilon. This allows
+		HDBSCAN to find clusters of varying densities (unlike DBSCAN), and be more
+		robust to parameter selection.
+
+		In practice this means that HDBSCAN returns a good clustering straight away
+		with little or no parameter tuning -- and the primary parameter, minimum
+		cluster size, is intuitive and easy to select. HDBSCAN is ideal for
+		exploratory data analysis; it's a fast and robust algorithm that you can
+		trust to return meaningful clusters (if there are any).
+	</longdescription>
+	<upstream>
+		<remote-id type="github">scikit-learn-contrib/hdbscan</remote-id>
+	</upstream>
+</pkgmetadata>