diff --git a/sci-biology/afni/ChangeLog b/sci-biology/afni/ChangeLog
new file mode 100644
index 0000000..1b58f60
--- /dev/null
+++ b/sci-biology/afni/ChangeLog
@@ -0,0 +1,4 @@
+*afni-9999 (09 Jan 2021)
+
+  09 Jan 2021;  <chymera@gentoo.org> +afni-9999.ebuild, +metadata.xml:
+  sci-biology/afni: new ebuild for CMake install
diff --git a/sci-biology/afni/Manifest b/sci-biology/afni/Manifest
new file mode 100644
index 0000000..a33f2ef
--- /dev/null
+++ b/sci-biology/afni/Manifest
@@ -0,0 +1,3 @@
+DIST 5eae81ba1e87ef3553df3b6ba585f12dc81a0030.tar.gz 107702 SHA256 a89e657385cfc5c7631bf34d21282f3720bf243337c99d42db99332f408f4fcd SHA512 c87712c0f334e025d29d1372ddbd7299b8d5378f7ef7dc09941a10f2f9c75ad9350fe8ceb6e0f6197a5f1c27ab79e03fdfb28a97582e860c6e667b29e9b75459 WHIRLPOOL ad303ee73431054ac97f49a544280bbc847f62b0e8b9fb9d0702197fa80856fd560b03606988ef3a875e43f0a56d92b55f8fbcc333079273266900443d1b768f
+DIST 65f801b9c2f1f15f4de4a19d45e6595c25765632.tar.gz 435886 SHA256 80cbfdfb24f8848de652a062be4f5c271d7858d643af4a939b6815306194144b SHA512 be03cdc6cf17fd9ff74c5ecc1f6b2132121bb4b7973a731da334af2a8428d1f0dbbf7b94b2511d1ff7e515b8cc4cf3316d62b189566fb6ffc88c6146eebd48ff WHIRLPOOL 4a3d8154ffa0500c27af2a4ccb60d0eb79ee661918023bd3dee223272e7aee1d360637f99e31414ffac105291fbc80d1f1a4b0c42b2d9fcf4a3c2c976d1ce37e
+DIST 962155a01f5a1b87bd64e3e3d880b4dbc2347ac7.tar.gz 881944 SHA256 6aa544799dafaa07c976d137088828262957e0ff5bd2bc6b856ba771c8944299 SHA512 47c1888758020bcf881e7a4933eec1716118c671ac1a9bb4f4637a9634f7fd5c3b5bfa4da7fa001c2bc6abd0f2469583c1275c398836b5c77cb870507c8e7df2 WHIRLPOOL a076721deb6cf206e05df37d10acdef2522be51b1889557319e60ccf8d0b89ba2030ec7f9297bd218c651d2875c661eec1f672d944cca8f3c46989b761201210
diff --git a/sci-biology/afni/afni-9999.ebuild b/sci-biology/afni/afni-9999.ebuild
new file mode 100644
index 0000000..16c69f6
--- /dev/null
+++ b/sci-biology/afni/afni-9999.ebuild
@@ -0,0 +1,104 @@
+# Copyright 1999-2021 Gentoo Authors
+# Distributed under the terms of the GNU General Public License v2
+
+EAPI=7
+
+#CMAKE_MAKEFILE_GENERATOR="emake"
+PYTHON_COMPAT=( python3_{6..8} )
+
+inherit cmake distutils-r1 git-r3 multilib
+
+GTS_HASH="962155a01f5a1b87bd64e3e3d880b4dbc2347ac7"
+NIFTI_HASH="65f801b9c2f1f15f4de4a19d45e6595c25765632"
+GIFTI_HASH="5eae81ba1e87ef3553df3b6ba585f12dc81a0030"
+
+DESCRIPTION="Advanced Normalitazion Tools for neuroimaging"
+HOMEPAGE="http://stnava.github.io/ANTs/"
+SRC_URI="
+	https://github.com/leej3/gts/archive/${GTS_HASH}.tar.gz
+	https://github.com/NIFTI-Imaging/nifti_clib/archive/${NIFTI_HASH}.tar.gz
+	https://github.com/NIFTI-Imaging/gifti_clib/archive/${GIFTI_HASH}.tar.gz
+	"
+EGIT_REPO_URI="https://github.com/afni/afni.git"
+
+SLOT="0"
+LICENSE="GPL-3+"
+KEYWORDS="~amd64 ~x86"
+IUSE="test"
+RESTRICT="!test? ( test )"
+
+RDEPEND="
+	dev-libs/glib:2
+	dev-libs/libf2c
+	dev-libs/expat
+	dev-util/ninja
+	media-libs/freeglut
+	media-libs/glu
+	media-libs/netpbm
+	media-libs/qhull
+	media-video/mpeg-tools
+	sci-libs/gsl
+	sys-devel/llvm:*
+	sys-libs/libomp
+	dev-libs/libpthread-stubs
+	virtual/jpeg-compat:62
+	x11-libs/libGLw
+	x11-libs/libXft
+	x11-libs/libXi
+	x11-libs/libXmu
+	x11-libs/libXpm
+	x11-libs/libXt
+	x11-libs/motif[-static-libs]
+	"
+DEPEND="
+	${RDEPEND}
+	app-shells/tcsh
+	"
+# Prospectively:
+#sci-libs/gts
+#Update jpeg-compat to virtual/jpeg:0
+# look for xmhtlm
+
+src_prepare() {
+	tar xf "${DISTDIR}/${GTS_HASH}.tar.gz" || die
+	tar xf "${DISTDIR}/${NIFTI_HASH}.tar.gz" || die
+	tar xf "${DISTDIR}/${GIFTI_HASH}.tar.gz" || die
+	cmake_src_prepare
+	default
+	}
+
+src_configure() {
+	#LDFLAGS="-L${S}/${LIBDIR} ${LDFLAGS}" econf --enable-progpath="${EPREFIX}/usr/bin"
+	export CFLAGS="-pthread ${CFLAGS}"
+	#export LDFLAGS="-lpthread ${LDFLAGS}"
+	#-CC="$(tc-getCC)"
+	local mycmakeargs=(
+		-GNinja
+		-DCOMP_BINARIES=ON
+		-DUSE_SYSTEM_NIFTI=OFF
+		-DUSE_SYSTEM_GIFTI=OFF
+		-DUSE_SYSTEM_XMHTML=OFF
+		-DUSE_SYSTEM_GTS=OFF
+		-DFETCHCONTENT_SOURCE_DIR_GTS="${WORKDIR}/${P}/gts-${GTS_HASH}"
+		-DFETCHCONTENT_SOURCE_DIR_NIFTI_CLIB="${WORKDIR}/${P}/nifti_clib-${NIFTI_HASH}"
+		-DFETCHCONTENT_SOURCE_DIR_GIFTI_CLIB="${WORKDIR}/${P}/gifti_clib-${GIFTI_HASH}"
+		-DCOMP_GUI=ON
+		-DCOMP_PLUGINS=ON
+		-DUSE_OMP=ON
+		-DCOMP_PYTHON=OFF
+	)
+	tc-export CC
+	cmake_src_configure
+}
+#/work/afni-9999/nifti_clib-65f801b9c2f1f15f4de4a19d45e6595c25765632
+
+#src_install() {
+#       BUILD_DIR="${WORKDIR}/${P}_build/ANTS-build"
+#       cmake_src_install
+#       cd "${S}/Scripts" || die "scripts dir not found"
+#       dobin *.sh
+#       dodir /usr/$(get_libdir)/ants
+#       insinto "/usr/$(get_libdir)/ants"
+#       doins *
+#       doenvd "${FILESDIR}"/99ants
+#}
diff --git a/sci-biology/afni/metadata.xml b/sci-biology/afni/metadata.xml
new file mode 100644
index 0000000..acf637d
--- /dev/null
+++ b/sci-biology/afni/metadata.xml
@@ -0,0 +1,16 @@
+<?xml version="1.0" encoding="UTF-8"?>
+<!DOCTYPE pkgmetadata SYSTEM "http://www.gentoo.org/dtd/metadata.dtd">
+<pkgmetadata>
+	<maintainer type="person">
+		<email>gentoo@chymera.eu</email>
+		<name>Horea Christian</name>
+	</maintainer>
+	<maintainer type="project">
+		<email>sci@gentoo.org</email>
+		<name>Gentoo Science Project</name>
+	</maintainer>
+	<longdescription>
+		Analysis of Functional NeuroImages (AFNI) is an open-source environment for processing and displaying 
+		functional MRI data—a technique for mapping human brain activity.
+	</longdescription>
+</pkgmetadata>